In an effort to discover small organic inhibitors that block gp41 activation, we have generated a biased combinatorial chemical library of non-natural binding elements targeted to the gp41 core.

Purpose: This study aims to investigate the efficacy and safety of PD-1/PD-L1 inhibitors in the first-line treatment of esophageal squamous cell carcinoma (ESCC) and identify factors influencing ...

Our results prove the potential of terphenyllin as a STAT3 inhibitor in the treatment of gastric cancer, which will provide a basis for the further development of this natural compound as a targeted ...