本研究揭示了P II 蛋白通过双重调控机制控制铁唯一固氮酶（Fe-only nitrogenase）表达的新范式：在氮限制条件下，尿苷酰化GlnK2 UMP 激活anfA转录；在氮充足时，去尿苷酰化GlnK1通过GAF结构域结合抑制AnfA活性。这一发现为开发不依赖钼（Mo）的生物固氮菌肥提供了关键 ...

Mutations or deletions in the gene for POLG yield defective polymerases that cannot stay on the mtDNA template, thus leaving the enzyme’s tasks incomplete. PZL-A binds to an allosteric site on ...

This useful study presents computational analyses of over 5,000 predicted extant and ancestral nitrogenase structures. While the data and some analyses are solid, the study remains incomplete in ...

Your body produces the enzyme creatine kinase (CK) or creatine phosphokinase to keep your muscles functioning properly. Healthcare providers use the CK test to check levels of this protein in your ...

A high bilirubin level, or hyperbilirubinemia, occurs when bilirubin has accumulated in your body in excessive amounts. Bilirubin forms when red blood cells break down at the end of their life cycle, ...

Enzymes are present in microorganisms, plants and animals and act as catalysts in various chemical reactions. This means that they increase the rate of the reactions. Because of this they can be ...

Luckily, there are supplements containing the lactase enzyme available which aid in lactose breakdown in the small intestine, providing potential relief. When searching for the best lactase enzyme ...

Bromelain is an enzyme mixture found in pineapples. It has various potential health benefits, including reducing inflammation and improving digestion. There is scientific evidence surrounding the ...

After many failed attempts, the experts realized they needed a new strategy. The breakthrough came with a small but powerful idea. They introduced goose lipases – natural enzymes used by birds to ...