Scientists at the University of Colorado Anschutz Medical Campus have found what might be a major cause of the memory ...

This article focuses on the role of protein post-translational modifications in hepatic ischemia-reperfusion injury, including phosphorylation, ubiquitination, acetylation, ADP-ribosylation, ...

NO SIGNALING:© 2003 Annual ReviewsAll images redrawn from D. Boehning, S.H. Snyder, Ann Rev Neurosci, 26:105–31, 2003.Neuronal nitric oxide synthase (nNOS) is localized to NMDA receptors by the ...

At the center of this breakdown is a rogue chemical change. It's called S-nitrosylation. In this reaction, nitrogen and oxygen attach to sulfur on key proteins, disrupting how they work.

But in the brains of people with Parkinson’s and LBD, the researchers discovered that p62 is being changed by a process called S-nitrosylation. This chemical reaction, caused by nitric oxide ...