In this work, we investigate the ability of TDG to excise modified nucleobases from the simplest unit of compacted DNA, the nucleosome core particle (NCP). We measure TDG activity on a population of ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

Objective: Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse ...

WASHINGTON, April 8 (Reuters) - U.S. President Donald Trump said on Tuesday the United States is taking in $2 billion per day from tariffs. He made the comment without providing details during an ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Locusts, as devastating pests, can reversibly ...

Note: This article contains spoilers about the show “Adolescence.” In just three weeks, the British crime drama “Adolescence” became the ninth most-watched Netflix series of all time. It’s not hard to ...

迈威生物（688062.SH），一家全产业链布局的创新型生物制药公司，宣布其靶向 B7-H3 ADC 创新药（研发代号：7MW3711）获 NMPA 批准开展联合 PD-1 抑制剂 ...

All 3 clinical studies use Nu.Q NET test to measure circulating levels of H3.1 nucleosome in the bloodstream. These serve as an excellent surrogate marker of neutrophil CL traps. All 3 studies ...