It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age ...

Scientists and researchers around the globe are investigating a series of mysteries about what happens to our bones over time.

Cornell research could rebrand bone as an extension of the nervous system and reshape the understanding of its cellular ...

AGEs, such as carboxymethyl lysine (CML), impair osteocyte function by activating the receptor for advanced glycation end products (RAGE), triggering oxidative stress and inflammatory responses. This ...

AGEs, such as carboxymethyl lysine (CML), impair osteocyte function by activating the receptor for advanced glycation end products (RAGE), triggering oxidative stress and inflammatory responses. This ...

A federally funded research team led by Sheri Holmen, PhD, investigator at Huntsman Cancer Institute and professor in the Department of Surgery at the University of Utah (the U), is testing a new ...

Excessive osteocyte death is found in various bone diseases, such as postmenopausal osteoporosis (PMOP), and osteoclasts are found increased and activated at osteocyte death sites. Currently, apart ...

“What’s the sport where the super athletic crazy guys jump on walls and scale them like a lizard?” Asked Ophelia at one of her morning training sessions. “You know, you see stunt men do it ...

Since our discovery in 2013 that genetic defects in PLS3 lead to bone fragility, the mechanistic details of this process have remained obscure. It has been established that PLS3 variants cause ...

Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key determinant of overall bone formation and bone mass. Despite extensive studies showing the function of ...

Most bones in mammals display a limited capacity for natural large-scale repair. The ribs are a notable exception, yet the source of their remarkable regenerative ability remains unknown. Here, we ...