A new research paper was published in Aging (Aging-US) on March 18, 2025, in Volume 17, Issue 3, titled “Mitochondrial ...

" [...] our work suggests that increased mtROS or decreased Atg7-dependent autophagy in osteoblastic cells, as well as reduced osteocyte dendrite number – common features of aged bone – do not ...

Targeting the HIF1α-HMOX1 axis could offer a novel approach to reducing osteocyte death and preserving bone integrity, thus improving the prognosis for melanoma patients with bone metastasis.