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研究人员针对阿尔茨海默病（AD）轴突球状体机制不明问题，经多方法研究，发现关键机制及潜在治疗靶点。 阿尔茨海默病（Alzheimer’s disease，AD），这个让人谈之色变的神经退行性疾病，如同隐匿在大脑中的 “记忆窃贼”，无情地偷走患者的认知和记忆。随着全球老龄化加剧，其发病率不断攀升，给无数家庭带来沉重负担。在 AD 的病理特征中，β - 淀粉样蛋白（Aβ）肽聚集形成的细胞外沉积物，以及 ...

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York County Coroner’s Office is investigating a death at Piedmont Medical Center after an incident at Meritor, Inc. on Friday.

International Cooperation Base for Active Substances in Traditional Chinese Medicine in Hubei Province, School of Pharmaceutical Sciences, South-Central Minzu University, 182 min-Zu Road, Wuhan 430074 ...

Background: Diabetes mellitus (DM) is a metabolic disease with high morbidity, which significantly affects human life and health expenditures. Previous studies have demonstrated that artemether (ATM) ...

此外，miR - 205 模拟物或 miR - 205 - Exos 处理导致巨噬细胞中 PTEN 表达降低，p - AKT、p - mTOR 和 p - 4EBP - 1 表达增加，且该效应可被 PTEN 表达逆转。使用 PI3K 抑制剂 GDC - 0941、AKT 抑制剂 MK - 2206 和 mTOR 抑制剂雷帕霉素（rapamycin）阻断 PI3K/AKT/mTOR ...

In lung carcinoma, loss of CMTM4 significantly reduces tumor growth and impairs NF-κB, mTOR, and PI3K/Akt pathway activation. Furthermore, we demonstrate that CMTM4 can regulate epidermal growth ...

Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China Department of Molecular, ...