SickKids researchers identified the KCNB2 gene as a key driver of medulloblastoma tumor growth. Blocking KCNB2 disrupts potassium channels, causing tumor-propagating cells to swell and lose integrity.

Our collaborators at the Institut Curie, Paris and NCNP, Tokyo have shown that signalling through the non-receptor tyrosine kinase SRC is upregulated in Group 4 medulloblastoma and furthermore, that ...