为解决结直肠癌（CRC）转移机制不明及缺乏有效治疗靶点的问题，研究人员开展了 NR3C2-SIRT1 信号轴在 CRC 转移机制中作用的研究。结果发现该信号轴促进自噬、抑制上皮 - 间质转化（EMT），抑制 CRC 肺转移，为 CRC 治疗提供潜在靶点。

Edited by Ana Maria Cuervo, Albert Einstein College of Medicine, Bronx, NY; received June 7, 2024; accepted February 26, 2025 ...

This break may allow it to focus energy elsewhere, such as on repairing the body. The concept of autophagy is also popular with proponents of intermittent fasting. In the simplest terms ...

Additional programs included in the exemption are P21 million for the City Agriculture Department, P7 million for the Division for the Welfare of the Urban Poor, P7.5 million for the Department of ...

How about medicine, the payment for electricity, and water?) The senatorial candidate added that managing the per kilo price of rice would be a big help to many Filipinos, which currently averages P46 ...

Abnormal autophagy is a key factor in the development of AS ... China); NF-κΒ activator 1 was purchased from MedChemExpress (Shanghai, China); Antibodies against Beclin1, LC3B, P62, CD31, VEGF, TNF-α, ...

COTABATO CITY — Sixteen Bangsamoro lawmakers provided hospitals and rural health units (RHUs) in the autonomous region with P62.1 million worth of financial support, ambulances and other ...

While fasting is primarily a spiritual discipline, modern scientific research highlights its remarkable health benefits, particularly through a process known as Autophagy. The term autophagy, derived ...

On the first day, the researchers found clear signs of stress. Cells showed an increase in proteins like p62, which typically accumulate when autophagy is disrupted. LC3-II, a marker of autophagic ...

One key protein they found being affected is called p62. This protein normally plays a major role in helping autophagy work properly, guiding harmful waste like alpha-synuclein to be removed from ...