南昌大学第二附属医院邵江华团队在《Cell Death and Disease》发表的研究，首次揭示了负调控泛素样蛋白1(NUB1)通过NEDD8-PCNA轴抑制HCC增殖的分子机制。 研究采用60例HCC临床样本队列，结合Western blot、免疫共沉淀(Co-IP)、免疫荧光等技术，构建NUB1基因修饰细胞株及裸鼠 ...

(A) WB revealed that EGFR was activated by recombinant ... (J, K) Immunofluorescence staining of Ki67 and PCNA in liver sections from DMSO (n = 3) and gefitinib (n = 3) rats at 48 h after PVL.