Liver injury is an independent risk factor for multiple organ dysfunction and high mortality in patients with sepsis. However, the pathological mechanisms and therapeutic strategies for ...

A systematic review published in Discover Oncology explores the anticancer efficacy of medicinal plant extracts in treating Oral Squamous Cell Carcinoma (O | Plants And Animals ...

The biomarker analysis found patients with certain mutations in the PI3K/AKT/mTOR pathway and MAPK pathway may be resistant to Truqap.

Q4 2024 Earnings Call Transcript March 31, 2025 Celcuity Inc. misses on earnings expectations. Reported EPS is $-0.85 EPS, expectations were $-0.72. Operator: Good afternoon, ladies and gentlemen, and ...

Celcuity Inc. (Nasdaq: CELC), a clinical-stage biotechnology company pursuing development of targeted therapies for oncology, today announced that Brian Sullivan, Chief Executive Officer, and ...

Three interconnected signaling pathways: estrogen's cyclin D1, CDK4/6 and PI3K-AKT-mTOR pathways promote this disease. And we believe that simultaneous blockade of all 3 of these pathways offers ...

MINNEAPOLIS, March 31, 2025 (GLOBE NEWSWIRE) -- Celcuity Inc. (Nasdaq: CELC), a clinical-stage biotechnology company pursuing development of targeted therapies for oncology, today announced financial ...

Kazia to receive USD $1 million from Vivesto for the intellectual property and trademark assets rights to the oncology drug candidate, Cantrixil SYDNEY, March 31, 2025 /PRNewswire/ -- Kazia ...

Oxidative stress activates the PI3K/AKT pathway by inhibiting PTEN, regulating BMAL1 in an mTOR-dependent manner, revealing the intricate interactions among oxidative stress, PI3K/AKT signaling ...

PI3K, AKT, and mTOR inhibitors – The survival blockers The PI3K/AKT/mTOR pathway is a regulator of cancer cell growth and survival, making it a target of choice. Several drugs have already made a ...