研究证实华蟾素能抑制结直肠癌生长，经网络药理学、多组学及模型验证，确定其通过8个关键成分作用于6个核心靶点，抑制 ...

Introduction: Phosphoinositide 3-kinase (PI3K), Phosphatase and tensin homolog (PTEN) and connexin50 (Cx50) have individually been shown to play critical roles in the growth, development and ...

Owing to its high mortality rate, lung cancer (LC) remains the most common cancer worldwide, with the highest malignancy diagnosis rate. The phosphatidylinositol-3-kinase (PI3K)/protein kinase B (AKT) ...

A unique dataset of Type Ia supernovae being released today could change how cosmologists measure the expansion history of the universe. Type Ia supernovae are the dramatic explosions of white ...

The current PI3K 3C inhibitors in use in advanced breast cancer are alpelisib and inavolisib. Capivasertib is an AKT inhibitor, which is also used in PI3K 3C mutated breast cancer. So these are ...

Editor’s note: This is an automatically generated transcript. Please notify [email protected] if there are concerns regarding accuracy of the transcription. There are several clinical trials ...

Black bars show potentially Akt-related genes. Asterisks show dynamics concordant with the Nef-G63E phenotype (PI3K-pAkt Ser473 downstream downregulation or inhibition upregulation). MFIs relative to ...

刚刚结束的巴黎人工智能峰会称促成了法国多项投资和国际合作计划，将支持IA 这个在过去两年中颠覆了整个社会领域的技术发展。 据法新社今天称 ...

Microsoft is working across many fronts to make the promise of AI real, and here you’ll find the resources, information and access to help media outlets, journalists and influencers bring their ...