Researchers have unveiled the first real look at a mitochondrial protein strongly linked to Parkinson's disease, revealing ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

(IN BRIEF) Researchers at the Institute of Cancer Research in London have identified genetic markers that predict a significant survival benefit from combining ipatasertib with abiraterone in treating ...

However, when the researchers looked more closely at the most common genetic alterations across the patients’ tumour samples, they were able to associate certain characteristics with better or worse ...

As genetic and biomarker tests become more common, so do new therapies that target specific tumor types and may lead to ...

The researchers predicted that the new tool will enable the development of personalized therapeutics by monitoring PTEN activity in various biological settings.

PTEN is a gene that helps control cell growth. An inherited change in PTEN can cause Cowden syndrome, a disorder that puts you at risk for cancerous and noncancerous breast tumors and other growths.

They're given to women who have a mutation in the BRCA gene and HER2-negative breast cancer ... have changes in any of the AKT1, PIK3CA, or PTEN genes. Everolimus (Afinitor).

They include familial medullary thyroid carcinoma (RET gene), familial adenomatous polyposis (APC gene), Cowden disease (PTEN gene), Carney complex type 1 (PRKAR1A gene), nonfamilial medullary thyroid ...

Proper control of cell growth is especially crucial in early brain development, particularly within the first few years of life. A key regulator of this process is the Phosphatase and Tensin Homolog ...

Genetic predisposition is one of the strongest risk factors for developing asthma. While no one is born with asthma, you may be born with genes that dictate whether you’ll get it as an infant or ...