Common anticancer drugs may offer new hope to PTEN Hamartoma Tumor Syndrome patients
During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner. Many ...
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Targeted cancer cell therapy may slow endometrial cancer
"ERBB2 and PTEN are a part of different signaling pathways, but we believe they have a correlation in endometrial cancer," Dunston said. "The effect of ERBB2 targeting on endometrial cancer with ...
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Why some breast cancer treatments stop working
Mutations in PIK3CA and loss of PTEN contribute to its hyperactivation. The Wnt/β-catenin pathway promotes EMT and metastasis, driven by Wnt signaling through LRP5/6 and β-catenin, which ...
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New insights into therapy resistance in breast cancer
A new review was published in , Volume 16, on March 13, 2025, titled "Signaling pathway dysregulation in breast cancer." ...