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AP Biosciences, a clinical-stage biopharmaceutical company dedicated to transforming cancer therapy through innovative bispecific antibodies, today announced the presentation of new preclinical data ...
Macrophages salvage nutrients from the bacteria they phagocytose to regulate inflammatory responses, revealing ...
A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human ...
这项研究首次确定了CD47水平在自闭症中的异常升高,并证明阻断其信号通路可以增强小胶质细胞的吞噬功能,减少突触数量,进而缓解自闭症小鼠的社交障碍。这意味着,针对CD47的治疗方法可能具有潜在的临床应用价值,为自闭症的治疗提供了新的方向。
Get Instant Summarized Text (Gist) A novel approach using CAR-M (Chimeric Antigen Receptor Macrophages) has been developed to address the limitations of CAR-T therapy in treating solid tumors. By ...
Recent innovations include engineering CAR T-cells to overcome the immunosuppressive tumour microenvironment and enhancing their ability to infiltrate solid tumours.