Changes are coming to the cold and cough aisle of your local pharmacy: U.S. officials are moving to phase out the leading decongestant found in hundreds of over-the-counter medicines, concluding ...
2020). 1-methyl4-phenyl-1,2,3,5-tetrahydropyridine (MPTP) and 1-methyl-4-phenyl pyridinium (MPP +) are well-known neurotoxins. MPP +, the active metabolite of MPTP, is transported into dopaminergic ...
2013). CYP epoxygenases generate linoleic epoxides including 9,10-epoxyoctadecenoic acid (9,10-EpOME) and 12,13-epoxyoctadecenoic acid (12,13-EpOME), which are further metabolized by soluble epoxide ...
Tetrahydrofuran (THF) (Wako Chemical, Osaka, Japan, 99%) and pyridine (Kanto Chemical, Tokyo, Japan, 99.5%) were distilled over sodium wire before use. Other materials were used without any ...