This is the first study to demonstrate the effects of strain alone on tau protein can cause aggregation. Future studies will need to address how phosphorylated tau behaves and whether specific ...

Despite its wide acceptance, a number of observations caused us to question the prevailing model: (1) Affinity of the tSH2 domain for phosphorylated CTD-derived peptides is weak under physiological ...

In principle, if different sites on a particular protein were phosphorylated with very different kinetics ... And a set of four SH2 domains including EAT2, SHP2-N and the only two Src-family kinases ...