Nucleotide databases like NCBI nt have a broad range of applications, from diagnosing infection and tracking disease to monitoring environmental health, studying microbiomes and developing ...

Add a description, image, and links to the nucleotide-substitution-models topic page so that developers can more easily learn about it.

diff uses to salvage the pyrimidine nucleotide uracil from a related compound: 4-thiouracil. They showed that 4-thiouracil gets incorporated into RNA and is toxic to resident gut microbes that do ...

diff uses to salvage the pyrimidine nucleotide uracil from a related compound: 4-thiouracil. They showed that 4-thiouracil gets incorporated into RNA and is toxic to resident gut microbes that do ...

diff uses to salvage the pyrimidine nucleotide uracil from a related compound: 4-thiouracil. They showed that 4-thiouracil gets incorporated into RNA and is toxic to resident gut microbes that do ...

The data show that in individuals with TK2d who were aged 12 years or less when their symptoms first appeared, treatment with pyrimidine nucleoside and/or nucleotide therapy significantly ...

BRUSSELS, March 19, 2025 /PRNewswire/ -- UCB, a global biopharmaceutical company, today announced positive data from studies involving its investigational pyrimidine nucleoside therapy, doxecitine ...

To multiply rapidly, cancer cells need to quickly manufacture DNA and RNA, which requires sufficient quantities of purines and pyrimidines. Upon analyzing the levels of 3,000 genes in a T cell ...

One reason cancer is so difficult to eradicate is its metabolic flexibility, she said. Her findings suggest that the salvage pathway could be an access route for cancer cells to get their nucleotide ...

The usage of expressed somatic mutations may have a unique advantage in identifying active cancer driver mutations. However, accurately calling mutations from RNA-seq data is difficult due to ...