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ATG5是自噬过程中最重要的蛋白质之一。在自噬过程中,ATG5与ATG12合作形成共价复合物,促进吞噬泡的形成。随着吞噬泡的不断延伸和扩展,细胞器和病原体等细胞成分被吞噬,最终形成自噬体。在atg5基因敲除小鼠中,铁沉积水平降低,而GSH水平和GPX ...
The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in ...
The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.
本次青岛农业大学植保前沿学术论坛为2025年第一期,旨在进一步加强学术交流,拓宽学术视野。植物医学学院将定期举办植保前沿学术论坛,邀请国内外一流专家学者来校进行学术报告和讲座,为师生提供更多与植物保护学科领域专家学者学习交流的机会,推动学术交流与学科 ...
2025年5月5日,北京大学生命科学学院伊成器教授与中科院遗传与发育生物学研究所王秀杰研究员合作,在《Nature Methods》期刊上发表了题为“Mild and ultrafast GLORI enables absolute ...
The interaction between circular RNA (circRNA) and RNA-binding protein (RBP). The approaches to RNA therapy targeting the circular RNA (cir ...
A new research paper was published in Oncotarget , Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis." In this study, researchers ...
Each cell has their own genetic code that helps maintain viability and directs function.  This genetic code is commonly referred to as deoxyribonuclei | Immunology ...
A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led ...
更重要的是,这种剧烈的核糖体“卡壳”效应完全依赖于m⁶A的存在。在Mettl14敲除细胞中,这些原本会引起剧烈“卡壳”的位点就几乎不引起核糖体富集了。这表明,m⁶A本身是导致核糖体剧烈“卡壳”的直接原因,而不是这些位点原本就有的“卡壳”倾向。
撰文丨王聪编辑丨王多鱼排版丨水成文在细胞这个精密运转的“微型城市”中,信使RNA(mRNA)分子如同快递包裹,承载着生命活动的核心指令,将来自 DNA 的遗传信息通过核糖体翻译为蛋白质,以执行生命活动。N6-甲基腺苷(m6A)是 mRNA ...
A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.