来自新加坡国立大学的张阳教授团队提出了一种基于深度学习的高精度 RNA 结构预测框架 DRfold2，集成了预训练的 RNA 复合语言模型和去噪结构模块，用于端到端的 RNA 结构预测，其在多个基准测试中，相较于其他最先进的方法表现出色。

RNA 是尚未开发的药物靶标的巨大宝库。基于结构的虚拟筛选 (VS) 利用结合位点信息识别候选分子，传统上采用分子对接模拟。然而，对接很难在大型化合物库和 RNA 靶标中扩展。

Discover how RNA therapeutics are reshaping medicine, offering new treatments for previously undruggable targets.

The "RNA Analysis Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F" report has been added to ResearchAndMarkets.com's offering.The Global RNA Analysis Market was ...

A research team led by Rice University’s Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a protein that regulates ribonucleic acid (RNA) induced immune responses. Their ...

A research team led by Rice University's Yang Gao has uncovered new insights into the molecular mechanisms of ADAR1, a ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...

hLife聚焦健康科学领域的前沿进展，旨在促进基础研究与临床应用的融合发展。期刊发表与医学相关各研究领域最新成果，学科领域包括（但不限于）病原生物学、流行病学、生理学、免疫学、结构生物学、疾病监测、肿瘤、药物、疫苗和健康政策等。