The Price to Earnings (P/E) ratio, a key valuation measure, is calculated by dividing the stock's most recent closing price by the sum of the diluted earnings per share from continuing operations ...

No writing assistance was utilized in the production of this manuscript. RANKL expression is stimulated in osteoblasts and osteocytes by cytokines and hormones, and plays an important role in ...

Looking today at week-over-week shares outstanding changes among the universe of ETFs covered at ETF Channel, one standout is the SPDR Bloomberg High Yield Bond ETF (Symbol: JNK) where we have ...

Osteonecrosis of the femoral head (ONFH) is a debilitating condition characterized by the death of bone cells in the hip joint, resulting in profound disability. This condition has a significant ...

Department of Pediatric Orthopedics, Children’s Hospital Affiliated to Xiangya Medical College of Central South University (Hunan Children’s Hospital), Changsha, 86 Ziyuan Road, Hunan 410000, P. R.

Pursuant to Regulation 32 of SEBI (LODR) Regulations, 2015, please find enclosed herewith the Statement of Deviation or Variation in utilization of funds raised through proceeds of IPO by the Company, ...

Regarding p-JNK, NEO significantly inhibited its expression level at 10 min ... Concerning IκB-α degradation phenomena, Western blot results indicated that NEO could not prevent RANKL-induced ...

TGF-β activates SMAD2/3 signaling to stimulate CXCL16 expression and SMAD2/3 and MEK signaling to stimulate LIF expression. Increases RANKL expression in vitro. S1P binding to its receptor leads to ...

Osteoimmunology highlights the two-way communication between bone and immune cells. T cell protein tyrosine phosphatase (TCPTP), also known as protein-tyrosine phosphatase non-receptor 2 (PTPN2), is ...

Blood flow to the affected tissue must be restored quickly if viability and function are to be preserved. We report that disruption of the mixed-lineage protein kinase (MLK) - cJun NH 2-terminal ...

Figure. Bone resorption in the skeleton often coexists with bone formation in the vasculature. A, Binding of RANKL to RANK stimulates osteoclast maturation and destruction of bone through loss of ...