BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Rheumatoid arthritis (RA) is known for causing all-over inflammation and pain. It happens when the immune system malfunctions and attacks the synovium, the lining of the joints. RA can target the ...

Differences between rheumatoid arthritis (RA) and ankylosing spondylitis (AS) include the joints they affect and who are most likely to develop each condition. Some treatments may work for one but ...

Astrocytes are notoriously two-faced—calmly coddling neurons one minute, then ruthlessly consuming their synapses the next. Why these dramatic mood swings? Blame the EphA4 receptor, according to a ...

The new chief medical officer of the Pulmonary Fibrosis Foundation speaks about patients in rural areas, research breakthroughs, the drug pipeline, and the Supplemental Oxygen Access Reform (SOAR) Act ...

Astrocytes are notoriously two-faced—calmly coddling neurons one minute, then ruthlessly consuming their synapses the next. Why these dramatic mood swings? Blame the Ephrin-A4 receptor, according to a ...

The RAS-MAPK system plays an important role in regulating various cellular processes, including growth, differentiation, apoptosis, and transformation. Dysregulation of this system has been implicated ...

These PMN-Ecto in turn suppressed C5a priming of the inflammasome and consequently inhibited IL-1β release and neutrophil influx. PMN-Ecto-mediated suppression required surface expression of the ...

2 Immunology Research Core Facility – Gemelli Science and Technology Park (GSTeP) - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy 3 Division of Clinical Immunology, Fondazione ...