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靶向 CCDC25 的 NET-DNA 抑制剂 di-Pal-MTO:抑制肿瘤进展并激活先天免疫 ...
结果发现 di-Pal-MTO 可抑制肿瘤转移、增强化疗效果并促进免疫激活,为乳腺癌治疗提供新策略。 中性粒细胞胞外陷阱(NET)的 DNA 成分(NET-DNA)与癌症转移和化疗耐药相关。不过,近期研究表明,NET-DNA 有助于激活树突状细胞(DC),并促进针对抗癌免疫的先天 ...
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