C&EN22 天
Pfizer readies its next-generation COVID-19 antiviral
Ritonavir binds with CYP3A4 enzymes, which are responsible for metabolism, and gives nirmatrelvir a pharmacokinetic, or PK, boost. Unfortunately, ritonavir can also boost the lifetime of other ...
WebMD3 年
Nintedanib/P-gp and Selected CYP3A4 Inhibitors Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. The ...
WebMD3 年
Selected Sensitive CYP3A4 Substrates/Schisandra Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment ...
The Hearty Soul on MSN9 个月
Woman Experiencing Burning Pains Turns Out To Have Medieval ‘Holy Fire' Disease
The woman was also taking ritonavir to treat HIV. This inhibited the enzyme CYP3A4, which caused serum levels of ergotamine ...
Monthly Prescribing Reference3 年
Emend Injection
Avoid concomitant moderate-to-strong CYP3A4 inhibitors (eg, azole antifungals, macrolides, nefazodone, ritonavir, nelfinavir, diltiazem) or strong CYP3A4 inducers (eg, carbamazepine, phenytoin ...