Chronic stress raises blood pressure. New research from Juntendo University, Japan, reveals that voluntary exercise prevents hypertension (high blood pressure) by restoring STAT3 levels in the ...

"In the amygdala, the gene Stat3 is involved in the regulation of blood pressure and possibly plays a role in blood pressure elevation in response to chronic stress. It might also be involved in ...

Previous approaches to inhibit STAT3 did not achieve the desired effect because they did not consider that STAT3 exists in two variants—encoded by the same gene but transcribed differently.