Bio-Path Holdings, Inc., (OTCQB:BPTH), a biotechnology company leveraging its proprietary DNAbilize® antisense RNAi nanoparticle technology to develop a portfolio ...
General and administrative expense for the year ended December 31, 2024 increased to $4.7 million, compared to $4.2 million for the year ended December 31, 2023 primarily due to increased salaries and ...
A drug typically prescribed for arthritis halts brain-damaging seizures in mice that have a condition like epilepsy, according to researchers at the University of Wisconsin–Madison.
Key Laboratory of Marine Drugs, The Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People’s Republic of China Key Laboratory of Marine ...
The invention also includes delivery mechanisms to enhance the bioavailability and efficacy of the inhibitors. EGFR, RAF1, and STAT3 Inhibitors Patent WO 2024160878 A1: This patent focuses on ...
Louis, MO 63132, USA; ddenardo{at}wustl.edu Results In KPC mice, the expression levels of phosphorylated STAT3 (pSTAT3) were increased in PDAC cells as they progressed on FAK inhibitor therapy. This ...
NT219 in combination with EGFR antibody cetuximab (Erbitux) is currently entering a Phase 2 study for head and neck cancer ...
IL-23R Inhibitor Peptide-1 可特异性结合 IL-23R,阻断 IL-23 与 IL-23R 的结合,从而抑制 IL-23R 介导的信号转导通路。例如,能阻止 IL-23 诱导的 STAT3 磷酸化,STAT3 是细胞内重要信号转导分子,其磷酸化被抑制后,相关基因表达受影响,细胞炎症因子分泌减少,进而抑制 ...