These biological responses to AZD1480 are associated with concomitant inhibition of phosphorylation of JAK2, STAT3 and MAPK signaling proteins. In addition, there is inhibition of expression of ...

They found a protein called STAT3, key to a cell signaling pathway called JAK ... "If you've had rheumatoid arthritis for ...

The U.S. Patent and Trademark Office granted a Notice of Allowance for a patent titled "P-ethoxy nucleic acids for STAT3 inhibition," and the New Zealand Intellectual Property Office awarded ...

NT219 in combination with EGFR antibody cetuximab (Erbitux) is currently entering a Phase 2 study for head and neck cancer ...