The nicotinic acetylcholine receptors (nAChRs) are the most well understood membrane receptors for neurotransmitters at the structural and functional level. They are integral allosteric membrane ...

Neurodiverse students, especially those with sensory processing differences, often face unique challenges in engaging with standard social and emotional learning (SEL) programs. While these programs ...

In order to instantly facilitate these bodily processes, highly specialized sensory and motor neurons (as well as interneurons) are used to transmit these signals and coordinate the way your body ...

While early haptic devices focused on single-sensory cues like vibration-based notifications ... Today's innovations focus on cutaneous feedback—stimulating the skin's receptors to provide realistic ...

This paper introduces a new class of machine learning models for capturing how likely a specific nucleotide in a rearranged IG gene is to undergo somatic hypermutation. These models modestly ...

Dan Berkowitz might never have noticed the phenomenon if not for the new lights. In 2012, Johns Hopkins University’s Berkowitz had just moved to a lab space where the lights were motion-activated, and ...

The usage of expressed somatic mutations may have a unique advantage in identifying active cancer driver mutations. However, accurately calling mutations from RNA-seq data is difficult due to ...

Microbiota regulate the tryptophan metabolism involved in serotonin production, serotonin acts as a key neurotransmitter in the CNS and ENS, and serotonin receptors play a pivotal role in the ...

Within this receptor family, the structural and functional diversity 6 has sparked interest in nAChRs as potential therapeutic targets to address various medical conditions, and has spurred drug ...

Here, we focused on the mechanisms controlling recovery from adult diapause. Here, we show that functional improvement of post-mitotic somatic tissues does not require germline signaling, germline ...

From the gut and airways to the blood, muscle, and skin, diverse sensory receptors are doing unconventional things. A series of rodent experiments showed that even with abundant food and water, ...