An RNA-Seq data exploration tool that shows read map coverage of a gene of interest along with a coloured "electronic fluorescent pictographic" (eFP) based on its RPKM expression level.

Surface markers (TRA-1-60, TRA-1-81, SSEA3, SSEA4) are easier to detect since the antigens are accessible to antibodies, while the detection of intracellular markers (Oct3/4, Sox2, Nanog) requires an ...

Differential RNA alternative splicing (AS) between vector transduction conditions was calculated from bulk RNA-sequencing using the rMATS (version 4.1.1) 70. Gene and transcript annotations were ...

卵巢癌死亡率高，化疗耐药是难题。研究人员聚焦 SOX2 阳性卵巢癌细胞，探究 AKT1 对其影响。结果发现抑制 AKT1 可下调 SOX2，增敏铂类药物。该研究为卵巢癌治疗提供新策略。 卵巢癌是女性健康的一大杀手，在妇科恶性肿瘤中致死率极高。这主要是因为卵巢癌 ...

This valuable descriptive manuscript builds on prior research showing that the elimination of Origin Recognition Complex (ORC) subunits does not halt DNA replication. The authors obtain solid data ...

近端（靠近气管）区域中，Sox2和Foxj1基因表达丰富；而在远端（靠近肺泡）区域，Sox9和Etv5基因则更为突出。这一发现有助于理解气道发育的空间 ...

Music creation platform Splice has acquired Spitfire Audio, the UK-based developer of high-end virtual instrument libraries. The acquisition marks Splice’s entry into the fast-growing plugin ...

Photo Credit: Matthew Johnson Paul Thomson, Co-Founder of Spitfire Audio and Kakul Srivastava, CEO of Splice. Splice — valued in 2021 at nearly USD $500 million after securing $55 million in funding – ...

Splice has confirmed that both companies will continue to operate independently "in the near term". Olivier Robert-Murphy will remain in place as Spitfire Audio's CEO, while Paul Thomson will continue ...