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基于结构的数字化药物研发 :水木药业基于自有冷冻电镜集群、GPCR平台和AI技术,全球第一个成功获取了新一代肥胖靶点GPR75的高分辨冷冻电镜结构,大幅提升了小分子药物发现和优化效率,有机会成为超越斯美格鲁肽的新一代减肥小分子药物。
The Structural Biology and Biophysics cluster provides graduate training in this exciting and important area for biomedical research that draws upon concepts and approaches from biology, chemistry, ...
Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...
In January 2004, Nature Structural Biology will be renamed Nature Structural & Molecular Biology. The title change effectively represents a 'relaunch' of the journal, and it formalizes our ...
These dynamic changes are quantative and can be used as structural markers to screen novel rexinoids for similar binding characteristics. We also correlate our results with more traditional molecular ...
Thesis and dissertation based Master of Science (MS) and Doctor of Philosophy (PhD) degrees are offered in Biology and Botany. Botany also offers the Master of Arts (MA) degree. Students in the ...
The scientists at Boston Biomedical combined the power of several techniques including X-ray crystallography, resonance energy transfer and molecular modeling to obtain a three-dimensional, atomic ...
Modern biological sciences are enriched by the revolution in structural biology. Advances in techniques such as electron microscopy (EM), X-ray crystallography and NMR, coupled with modern biophysical ...
We are a leader in structural biology — a field that sits squarely between the physical and life sciences — and our neuroscience program, which brings together researchers from psychology, biology and ...
In this webinar, our expert speakers will demonstrate how thermal and pressure stress changed the structure and melting point of two model proteins and resulted in the discovery of different ...
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