Northwestern University researchers have identified structural features in engineered cell receptors that correlate with variations in receptor function. Computational protein structure prediction ...

Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...

Cardiac structure and function were assessed by transthoracic echocardiography (Vevo ... PerkinElmer), as previously described. 23 The muscarinic receptor agonist carbachol (100 μM) was used as a ...

Sweet taste receptors in the heart: A new pathway for cardiac regulation New research shows that the heart can sense sweeteners and can increase the force of heart muscle contraction in response ...

Deviations from this tonic activity, including phasic bursts or pauses caused by region-selective excitatory input, neuromodulator, or neuropeptide release can exert strong influences on intrinsic ...

Spread the love Table of Contents Introduction Methodology Top 10 Biotech Giants Rising Stars (11-25) Innovators and ...

Plants are very important living things. They have lots of jobs, such as providing animals with food and releasing oxygen into the air. To survive and carry out these jobs, they all need three ...

Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research ...

除了上文中浅析的首创性小分子药物, 本年度批准上市的新药还有多款值得深入挖掘和分析, 例如, 显像药物氟 [18F]比哒嗪 (flurpiridaz F18)是用于心肌缺血和梗死诊断评估的新型正电子发射断层扫描心肌灌注成像示踪剂; IDH1/2双重抑制剂伏昔尼布 (vorasidenib)则是几十年来首个用于神经胶质瘤治疗的新分子, ...

David Tarlinton Faculty of Medicine, Nursing & Health Sciences Improving outcomes for patients with systemic lupus erythematosus Eric Morand Faculty of Medicine, Nursing & Health Sciences In situ ...