Northwestern University researchers have identified structural features in engineered cell receptors that correlate with variations in receptor function. Computational protein structure prediction ...

Sweet taste receptors in the heart: A new pathway for cardiac regulation New research shows that the heart can sense sweeteners and can increase the force of heart muscle contraction in response ...

In preliminary studies, we discovered that selected typical and atypical antipsychotic drugs interacted with virtually every biogenic amine receptor tested, in confirmation of many prior studies ...

University of California has described tropane derivatives acting as 5-HT2 and muscarinic receptor ligands reported to be useful for the treatment of psychiatric disorders, depression, ...

Figure 1. 3D-structure of the TCR-pMHC complex. (1G4 TCR bound to NY-ESO-1/HLA-A201, entry 2BNR (124) of the PDB). TCRα, TCRβ, MHC, and b2-microglobulin are colored in blue, cyan, orange, and green, ...

Weng and his team reveal that out of hundreds of animal species, amphibians, specifically frogs, have the highest number of bitter taste receptors, known as TAS2Rs. While humans have 25 TAS2Rs ...

Until recently, it has largely been assumed that G protein-coupled receptors (GPCRs ... and oligomerization are universal aspects of GPCR structure. Furthermore, while the functional role of ...

ANAVEX®2-73 is an orally available drug candidate designed to restore cellular homeostasis by targeting SIGMAR1 and muscarinic receptors. Preclinical studies demonstrated its potential to halt ...

The healthy cells receive a low dose or no radiation. Special scans can check whether your NET has these receptors. If your NET has somatostatin receptors, doctors can use these receptors to target ...

G protein-coupled receptors (GPCRs) are seven-transmembrane proteins that participate in many aspects of the endocrine function and are important targets for drug development. They transduce signals ...