SARS-CoV-2 infection induces syncytia formation, which promotes viral transmission. In this paper, the authors aimed to understand how host-derived inflammatory cytokines IL-1α/β combat SARS-CoV-2 ...

By inducing a non-canonical RhoA/ROCK signaling pathway, IL-1beta inhibits the ability of SARS-CoV-2 infected cells to fuse with uninfected cells and produce syncytia. Convincing evidence underlies ...

Glia employ controlled fluctuations in intracellular ions and messengers; intercellular fluxes of these molecules underlie long-range signaling in glial syncytia that occur (within seconds) in the ...