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21 天
《Nature Medicine》新诊断胶质母细胞瘤新辅助三联免疫检查点阻断疗法 ...
这一系列变化表明免疫细胞在肿瘤组织中的浸润和激活明显增强。 T 细胞受体(TCR) repertoire 和免疫细胞变化:对治疗前后肿瘤和血液标本的分析显示,新辅助 ICIs 治疗后,肿瘤中 TCRβ 和 TCRγ 的克隆数、Shannon 多样性指数和 Shannon 均匀性指数均显著增加 ...
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