People with the rare Li-Fraumeni syndrome (LFS) have a high risk of developing cancer. Almost all those affected will develop ...

What is TP53 and what role does it play in cancer? Medically reviewed by Marla Anderson, MD The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in ...

Researchers have discovered race-associated molecular differences in tumors that may impact the way patients with pancreatic ...

In a recent trial, researchers found that Xpovio plus chemo had activity in NSCLC patients with KRAS mutations other than ...

New Drug Research & Development Co. Ltd. has disclosed cellular tumor antigen p53 (TP53) (Y220C mutant) stabilizers reported to be useful for the treatment of cancer.

A new type of cluster analysis makes customised cancer screening tests possible. People with the rare Li-Fraumeni syndrome (LFS) have a high risk of developing cancer. Almost all those affected will ...

Association between proto-oncogene N-RAS transcript level and overall survival in node-negative muscle-invasive urothelial bladder carcinoma.

Enrollment on track in Phase 2 pivotal portion of PYNNACLE clinical trial evaluating rezatapopt as monotherapy in patients with TP53 Y220C and ...