In the past 5–10 years there has been a growing trend for substituting conventional 5-fluorouracil with the oral prodrug of 5-fluorouracil, capecitabine, in chemotherapy regimens. This regimen ...
It is notable that capecitabine compliance was monitored by counting returned tablets, and capecitabine, 5-FU or folinic acid monotherapy was permitted in the event of discontinuation of ...
The article by Graetz et al entitled “Leveraging Mobile Health to Improve Capecitabine Adherence Among Women With Breast Cancer: A Pilot Randomized Controlled Trial” (JCO Oncology Practice ...
During the first cycle of capecitabine development, three concomitant drugs were found to affect 5-FU clearance. [5] Paracetamol and morphine increased 5-FU clearance by 26% and 41%, respectively ...
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