"Although these drugs were developed to treat other disorders, including kidney disease, heart disease and high cholesterol, ongoing studies have shown they can reduce the risk of vision loss in ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to ...

Matthew Matasar, MD, discussed what the findings from the ELM-1 trial of odronextamab in diffuse large B-cell lymphoma mean ...

The Tam Kung Temple, on the top floor of a narrow building on Government Street, is the oldest Chinese temple in Canada ...

Seven-transmembrane receptors (7TMRs), also known as G protein-couple receptors, are the largest class of transmembrane receptors and a common target for therapeutics. Initially thought to signal ...

Consequently, targeting the cAMP signaling pathway emerges as a pivotal strategy for enhancing immune responses. Studies have revealed that α2-adrenergic receptors (α2-ARs) can inhibit adenylyl ...

Odronextamab is an investigational bispecific antibody that binds to CD20 expressed on the surface of B cells, and to CD3 receptor expressed on the surface of T cells. This results in local T-cell ...

Specifically, Auletta highlights the emerging science in stem cell transplants and cell therapies, including treatments like chimeric antigen receptor (CAR) T-cell therapy. He also discussed topics ...

This means it can activate those receptors without stimulating other ... Therefore, this new class of agonists could help ALKS expand its TAM in the long run. ALKS even has a program called ...

GLP-1 receptor agonists are pharmaceutical treatments primarily for T2D and more recently, obesity. They function by mimicking the action of GLP-1 hormone, which plays a crucial role in ...

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