These events are associated with innate training and can have long-term impacts on hematopoietic stem and progenitor cell (HSPC) development but can also compromise their function. While many ...

Here authors show that autophagy in CD4 T cells is an important process in preventing the emergence of pathogenic Th17 cells, which are causal to the progression of liver fibrosis. Adenoids and ...

This study aimed to investigate the signature genes and their association with immune cells in IVD degeneration. Methods: We analyzed differentially expressed genes (DEGs) in a dataset of IVD ...

在癌症免疫中，Th17 细胞作用存在争议且其向 Tregs 转分化机制不明。研究人员开展关于 NLRP3 在 Th17 细胞中作用的研究，发现 NLRP3 影响 Th17 细胞功能，缺乏 NLRP3 可抑制肿瘤生长。该研究为癌症免疫治疗提供新方向。 在癌症的复杂战局里，免疫细胞间的 “博弈 ...

Today, cell culture’s wide-ranging applications include genetic engineering, drug development and vaccine production. Although the foundational concepts and methods remain the same, the technology has ...

This colonization resistance displayed by female mice was mediated by an increase in IL-17A+ CD4+ T cells (Th17) and dependent on neutrophils. Ovariectomy of female mice increased MRSA burden, but ...

He decided to take a chance on a clinical trial at Mass Eye and Ear for a procedure that's the first of its kind in the U.S. "The name of it is cultivated autologous limbal epithelial stem cell ...

这项技术的核心在于利用稳定同位素标记的氨基酸（Stable Isotope Labeling by Amino acids in Cell Culture, SILAC）。简单来说，研究人员在细胞培养基中加入一种 ...

Genes regulating the finger-like cellular protrusions—filopodia have long been implicated in cancer metastasis. However, depleting the flat lamellipodia but retaining filopodia drastically hampers ...

Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), ...

Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, ...