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Proinsulin-transferrin (ProINS-Tf) fusion protein was evaluated for its in vivo pharmacokinetics, efficacy, and mechanism. Our previous studies have shown that ProINS-Tf was converted to active ...
DMG-PEG-Transferrin 是一种磷脂-PEG-蛋白质复合物,由 1,2-二肉豆蔻酸甘油酯(DMG)、聚乙二醇(PEG) 和 转铁蛋白(Transferrin) 组成。它结合了磷脂的膜融合能力、PEG 的生物相容性和转铁蛋白的靶向特性。 使用方法: 脂质纳米颗粒制备:将 DMG-PEG-Transferrin 与其他 ...
C18-PEG-Transferrin 是一种多功能化合物,结合了 C18烷基链、聚乙二醇(PEG) 和 转铁蛋白(Transferrin)。 C18烷基链: 一种长链疏水基团(十八烷基),具有强疏水性。 能够与脂质膜、疏水表面或疏水分子相互作用。 PEG链: 聚乙二醇(PEG)是一种亲水性聚合物 ...
Dyne anticipates filing a Biologics License Application (BLA) submission for US accelerated approval in early 2026.
Panchkula: A woman from Chandimandir filed a police complaint alleging that a man posing as an Army captain duped her and her ...
A significant proportion of children newly diagnosed with IBD present with anaemia, and many of them remain anaemic even ...
Researchers have found in a new study that in patients with heart failure and iron deficiency, ferric carboxymaltose did not ...
Transferrin receptor (TfR)-mediated transcytosis is a receptor-mediated mechanism for drug delivery to the brain or other tissues, where, after the antibody binds to transferrin, the therapeutic agent ...
The trial, called FAIR-HF2, enrolled 1,105 patients with HFrEF at 70 centers in six countries (Germany, Italy, Portugal, Slovenia, Hungary and Poland) All patients had iron deficiency at baseline, ...
Iron studies showed low serum iron, low serum transferrin and transferrin saturation. Liver function tests were mildly elevated. These results were suggestive of an inflammatory process in conjunction ...
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