RFK Jr. Takes On Food Giants: Calls Meeting With PepsiCo And General Mills 1 McDonald's menu sold adult collectible Happy Meal Rare hantavirus that killed Gene Hackman's wife surged in Arizona in ...

The manuscript contains important findings regarding inflammatory macrophage subsets that have theoretical and/or practical applications beyond the field of rheumatology. The authors demonstrate with ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The cGAS-STING signalling pathway has a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Stimulator of interferon genes (STING) is ...

This study investigated the role of TIPE2 in regulation of CD4 + T lymphocyte function in interaction of PHSML and TLR2/TLR4. Methods: The splenic CD4 + T cells were isolated from various mice (WT, ...

In particular, TLR4-dominant Gram-negative stimulation leads to a rapid type I IFN-mediated decline ... we propose a model based on studies involving quantitative binary ligand stimulation and intact ...

TLR4 activation initiates a signaling cascade leading to the production of type I IFNs and of the downstream IFN-stimulated genes (ISGs). Recently, a number of IFN-induced long non-coding RNAs ...