The researchers designed an efficient approach for fabricating engineered Pts-based nano-aircraft carriers with graded drug ...
Hyaluronidase naturally degrades hyaluronic acid, leading to issues with cells that produce myelin (the protective sheath ...
为探究结直肠癌(CRC)肿瘤微环境(TME)的异质性,研究人员分析 ECM,确定其细胞起源及与预后关系,意义重大。
Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy ...
A recent article in Small highlights a new method for studying tumor cell interactions and testing anti-metastatic drugs through the development of an Under-oil Open Microfluidic System (UOMS).
Tumors are held together by a structure called the extracellular matrix (ECM) that acts like the scaffolding around a building under construction. A team from The Institute of Cancer Research ...
Understanding the molecular cross-talk that occurs within the microenvironment between tumor cells and the ECM/other stromal cells may point to opportunities for cotargeting of the tumor and ...
Researchers at the University of California San Diego have uncovered a key mechanism underlying the treatment resistance of melanoma with the BRAF V600E mutation through pathways involved in focal ...
Non-cancer cells exist alongside the cancerous ones in the extracellular matrix (ECM), which is a network of different molecules in all tissues and organs that provide structure for the cells. The ECM ...
"Our work focused on fundamental understanding of ultrasound-mediated cancer cell killing and the effect of the ECM binding spacing on it," explains S Manasa Veena, Ph.D. student in BE and first ...