Vesicle uncoating requires ATP hydrolysis by auxilin-hsc70. The structure of many of the components of the clathrin machinery has been solved, and many of the protein-protein interactions have ...

COPI triggers vesicle formation at the Golgi, COPII works at the endoplasmic reticulum and clathrin acts at the plasma membrane. Lee and Goldberg now determine the structure of a COPI subcomplex ...