The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

根据协议，Chromatin Bioscience将运用其专有的 chromatinLENS 平台，设计与Astellas靶点特征相匹配的细胞选择性合成启动子。 设计的启动子有望在特定细胞类型中实现高度精确和持久的基因表达。

Using single-cell technologies, the researchers simultaneously analyzed the accessibility of genetic material through chromatin and the actual activity of relevant genes. Their findings reveal a ...

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct ...

April 3, 2025) Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this ...

A team led by Professor Kazuhiro Maeshima of the National Institute of Genetics (ROIS) and SOKENDAI in Japan has developed a method to visualize different types of chromatin and reveal their distinct ...

Jude Department of Structural Biology, revealed 13 distinct structures of the chromatin remodeler SNF2H offering a comprehensive view the process. (MEMPHIS, Tenn. – April 3, 2025) Chromatin ...

How chromatin openness controls behavioral changes remains unclear. This work implicates alternative promoter selection, ...