2025年3月24日,中国农业大学/神农种业实验室团队合作在国际知名期刊 International Journal of Biological Macromolecules 在线发表了题为 “Identification of the maize ...
The monocytic leukemia zinc-finger protein (MOZ) gene is rearranged in t(8; 16)(p11; p13) and inv(8)(p11q13) associated with acute myeloid leukemia. The other fusion partners involved are CBP and ...
Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired DNA sequence, and a DNA-cutting part of a restriction enzyme.
Zinc finger nucleases are designed to be like heat-seeking missiles, precisely targeted to find and cut specific sequences of DNA. Occasionally, however, they may snip the wrong spot, causing ...
Understanding of the DNA-binding characteristics of zinc-finger protein transcription factors has made it possible to design ZFPs to bind to specific target sequences and these designed ZFPs have been ...
A Bristol Myers Squibb Co. patent detailed new substituted phenyl oxooxazolyl piperidine dione molecular glue degraders acting as DNA-binding protein Ikaros (IKZF1), zinc finger protein Helios (IKZF2) ...
Figure 1 Left shows: Two zinc fingers in the DROSHA crystal structure. Right: A partial structure of the Microprocessor complex. Disclaimer: AAAS and EurekAlert! are not responsible for the ...