Cincinnati's Matt McLain hit his 2nd homer in as many days, and Nick Martinez was perfect for four-plus innings. But not perfect enough in a 6-3 loss.

Cincinnati, Ohio, USA; San Francisco Giants outfielder Heliot Ramos (17) high fives shortstop Willy Adames (2) after the victory over the Cincinnati Reds at Great American Ball Park. Mandatory Credit:

Takeaways From Cincinnati Reds Season-Opening Series Loss to the Giants. There were some positives, but the Reds are 1-2 after their first series of the season and yes, there are plenty of concerns after their disappointing start.

The San Francisco Giants head home after a 5-1 road trip, which included a three-game sweep of the Houston Astros.

After posting a sub-.500 road record in their first season under manager Bob Melvin in 2024, the San Francisco Giants entered this campaign pressed to start on a positive note away from Oracle Park. With their 3-1 interleague victory at the Houston Astros on Tuesday,

Pregame analysis and predictions of the San Francisco Giants vs. Houston Astros MLB game to be played on April 2, 2025 on ESPN.