为解决 EGFR 突变肺癌治疗中免疫逃逸和靶点选择难题，The Francis Crick Institute 等机构研究人员开展相关研究。发现治疗中克隆驱动新抗原会丢失，明确 WGD 前后突变特点。该研究为优化肺癌治疗策略提供依据，值得一读。 在肺癌的治疗领域，EGFR（表皮生长因子 ...

为攻克癌症治疗难题，研究人员合成新型喹啉衍生物，发现 4e 可抑制 EGFR 和 BRAF V600E ，有望用于抗癌。 癌症，这个如同恶魔般的存在，一直严重威胁着人类的健康。据国际癌症研究机构（IARC）2022 年全球癌症统计数据显示，当年新增约 2000 万癌症病例，970 万人 ...

During a live event, Alexander I. Spira, MD, PhD, and participants discuss efficacy, adverse events, and sequencing of ...

Pirker et al. 1 have published the results of a multinational phase III trial (FLEX; First-Line Erbitux in Lung Cancer) that randomly assigned 1,125 patients with chemotherapy-naive, EGFR ...

3月3日，NMPA发布的通知件显示，乐普生物的EGFR抗体偶联药物（ADC）维贝柯妥塔单抗（MRG003）收到药品通知件，这意味着其上市申请未获批准。

(the "Company") announced that the Company's trophoblast cell-surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC) sacituzumab tirumotecan (sac-TMT, formerly SKB264/MK-2870) was approved ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA highlighting the role of exosomal RNA (exRNA) in head and neck cancers (HNCs).

Related: Why do we have eyebrows and eyelashes? Evidence suggests that blocking EGFR may throw off the normal cycle of hair growth, extending the stage in which hair actively grows. Turning down ...

Results showed highest risks for CVD for low eGFR and high GFR. Overall, 214,111 patients developed CVD during the study. Glomerular hyperfiltration may increase CVD risks, including myocardial ...