Key suits were filed by third party mRNA and lipid pioneers that, while not having any mRNA-based products on the market themselves, leveraged their patent portfolios claiming a share of the ...

The surprise delay is casting new uncertainty on the fate of another vaccine awaiting FDA action: Moderna’s next-generation Covid-19 shot, called mRNA-1283, which is set for a decision by May 31.

为探究外源性信使核糖核酸（mRNA）的调控机制，研究人员开展了基于脂质纳米颗粒（LNP）包裹的体外转录 mRNA 的全基因组 CRISPR 筛选研究。结果发现硫酸乙酰肝素蛋白聚糖（HSPGs）等参与 LNP 摄取等过程，TRIM25 可抑制 mRNA，N 1 - 甲基假尿苷修饰能逃避其抑制。

As its name suggests, the tRNA then transfers the corresponding amino acid to the ribosome. This process repeats along the length of the mRNA strand until the ribosome runs into a stop codon, a ...

Ethris and Lonza agreed to collaborate on the development of room-temperature stable, spray-dried formulations of mRNA-based vaccine candidates, designed for mucosal delivery to combat respiratory ...

NEW YORK – The US Food and Drug Administration has cleared CureVac to begin a Phase I trial of its mRNA-based precision immunotherapy CVHNLC in patients with squamous non-small cell lung cancer, the ...

This is known as a mixed vaccine series. The National Advisory Committee on Immunization (NACI) recommends an mRNA vaccine (Pfizer-BioNTech Comirnaty ® or Moderna Spikevax ®) should be offered for ...

One likely explanation lies in the structure of the KEAP1 mRNA itself. The end of the transcript forms a distinctive shape that appears to attract the proteins needed for stop codon readthrough.

The United States led the world in developing the technology that beat the COVID-19 pandemic. Action from lawmakers may leave that legacy—and a $70 billion market—behind.

Get Instant Summarized Text (Gist) A novel class of zwitterionic phospholipids, specifically DOPE-Cx, significantly enhances mRNA delivery by facilitating endosomal escape, a major challenge in ...

What’s Up With mRNA Research? A research nurse holds an injection of a BioNTech mRNA cancer immunotherapy for non-small cell lung cancer. (Photo by Aaron Chown/PA Images via Getty Images ...