In recent years, mRNA technology enabled the rapid development of vaccines to fight COVID-19, saving millions of lives.

为探究自闭症谱系障碍（ASD）的分子机制，研究人员以 BTBR 小鼠为模型，开展前额叶皮层（PFC）的 mRNA 和 miRNA 表达谱研究。结果发现 1063 个差异表达基因和 48 个差异表达 miRNA，明确二者复杂关系。该研究为理解 ASD 发病机制及治疗提供新视角。

Advancements in mRNA vaccine technology are reshaping medicine, addressing challenges and expanding applications from ...

The following is a summary of “LncRNA-mRNA co-expression network in the mechanism of butylphthalide treatment for ischemic ...

Writing in Molecular Therapy Nucleic Acids, researchers hypothesized that using poly(A) tail mimetics to enhance mRNA expression from haploinsufficiency-associated genes could be a disease-modifying ...

This unique property facilitates membrane fusion-mediated endosomal escape, leading to improved mRNA expression in the liver compared to conventional phospholipids such as DSPC and DOPE.

丁苯酞作为一种神经保护药物，在治疗缺血性脑卒中方面展现出了潜力，它可以通过扩张脑血管、改善脑血流、减轻氧化应激等多种方式发挥作用。然而，其具体的作用机制却像一团迷雾，并不完全清楚。与此同时，信使核糖核酸（mRNA，作为蛋白质合成的模板，在生物过程中起着核心作用）和长链非编码核糖核酸（lncRNA，虽不编码蛋白质，但在基因表达调控中意义重大）在脑血管疾病的发生发展中扮演着重要角色，二者的共表达网络能 ...

The identification and intervention of Alzheimer's Disease (AD) in its early-stage allows for the timely implementation of lifestyle modifications and therapeutic strategies. Although dysregulation of ...