Delve into the kinase inhibitors' diverse landscape, from cancer breakthroughs to autoimmune disease innovations.
Oncology Small Molecule Drugs Market Expected to Grow Significantly Due to Industry Advancements. Growing Demand for Personalized Medicine and Target ...
Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid ...
The table is a review of notable updates that occurred in February 2025 for investigational products in development.
15 天
MedPage Today on MSNAdd-On Metformin Promising in ER-Positive Endometrial CancerAdding metformin to letrozole and abemaciclib (Verzenio) was tied to deep responses and prolonged progression-free survival (PFS) in some patients with recurrent estrogen receptor (ER)-positive ...
15 天
MedPage Today on MSNMixed Results for Therapeutic Candidates for Platinum-Resistant Ovarian CancerPromising therapies for platinum-resistant ovarian cancer produced mixed results in separate trials. The AKT inhibitor afuresertib failed to improve progression-free survival (PFS) when added to ...
这篇综述揭示了 GSK-3/β-catenin 信号轴对 ARHGAPs 的调控,及其在胶质瘤细胞迁移和侵袭中的关键作用。 一、研究背景 癌症细胞具有改变形态和进行表型转换的能力,这一过程在恶性肿瘤的发展中起着关键作用。在恶性脑肿瘤,如胶质母细胞瘤(GBM)中,癌细胞的 ...
Accepted for Priority Review Linvoseltamab (GSK) B-cell maturation antigen CD3 ... least 4 prior lines of therapy or those who received 3 prior lines of therapy and are refractory to the last ...
Pathological cardiac hypertrophy is the abnormal enlargement of the heart muscle in response to chronic stressors such as hypertension, myocardial infarction, or valvular disease. This maladaptive ...
Classical antidepressants have negative immunoregulatory and anti-O&NS effects, but their clinical efficacy is only marginally better than placebo. 5 Attenuating the JAK-STAT, NFκB, GSK-3, and TLR ...
GSK, Amgen and AstraZeneca released positive data supporting their rival drugs in a condition called chronic rhinosinusitis with nasal polyps, or CRSwNP.
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