Our study reveals the dual role of miR-263a, a conserved insect microRNA, in governing rice stripe virus (RSV) infection within both insect vector, small brown planthopper, and rice host. In the ...

研究人员采用了多种研究方法来探索肠道菌群与 AD 之间的关系。在动物模型方面，他们选用了多种 AD 小鼠模型，如 APP/PS1、5xFAD 等（这些模型分别模拟了 AD 的不同病理特征），通过对比不同处理组小鼠的表现，观察肠道菌群变化对 AD 相关病理的影响。在分析 ...

为探究阿尔茨海默病（AD）发病机制，山东第一医科大学第一附属医院研究人员对 5xFAD 雌性小鼠开展研究，发现 4 月龄小鼠记忆功能下降，海马区存在多种病理变化，为 AD 研究提供重要依据。 阿尔茨海默病（Alzheimer’s disease，AD），这个名字或许你并不陌生 ...

Department of Vascular Surgery, The Dingli Clinical Institute of Wenzhou Medical University (Wenzhou Central Hospital), Wenzhou City, Zhejiang Province 325000, China Laboratory of Wenzhou Pan-Vascular ...

Victor Ambros and Gary Ruvkun won this year’s Physiology or Medicine award for the discovery of microRNA and its role in post-transcriptional gene regulation. Danielle is a Senior Editor at The ...

Alterations in microRNA (miRNA) signaling have been implicated in the epigenetics and molecular genetics of all neurobiological processes associated with AD pathophysiology. These changes encompass ...

Therefore, we investigated chronic effects of AD-characteristic neurotoxic amyloid-β (Aβ) peptides as provided by transgenic overexpression (5xFAD mouse model) and acute effects due to oral ...